The strongest family in the Sicilian mafia is the Denaro faction and the strongest family in the Camorra is either the Contini or Mazzarella family. There are too many to say for the Ndrangheta. I would say the De Stefano, Piromalli, Nirta, Pesce or Barbaro families would be suitable answers. But it would be hard to narrow it down to just one or two.
