When you consider the lengthy demise of Sheeran and Buffalino (there's about 45 min. of movie left after Hoffa is killed) I think this is what Scorsese wanted to do differently this time. The frailty of an aging gangster. The isolation from a disapproving family. Once the money stops rolling in their friends are gone. The ones who die young just might be the lucky ones.
Good analysis Oak. That part of a gangster's life is typically ignored. Even Michael Franzese's interviews fall short of his expressing much in the way of regrets.