I'd read somewhere that Lucchese was the first NY boss to give Dragna the okay to take out Cohen. Beforehand, all the Jewish gangsters in Hollywood had been protected by the Commission. Giancana and Roselli were certainly instigators in that move, too.

"...the successful annihilation of organized crime's subculture in America would rock the 'legitimate' world's foundation, which would ultimately force fundamental social changes and redistributions of wealth and power in this country. Meyer Lansky's dream was to bond the two worlds together so that one could not survive without the other." - Dan E. Moldea