How did such an uber Harlem/Bronx outfit like the Luccheses end up with the Varrio crew way out in Brooklyn and Queens?

I'm reading Wiseguy again and was just wondering. The book doesn't really go into the Vario crew's formation in the Brownsville area.

"...the successful annihilation of organized crime's subculture in America would rock the 'legitimate' world's foundation, which would ultimately force fundamental social changes and redistributions of wealth and power in this country. Meyer Lansky's dream was to bond the two worlds together so that one could not survive without the other." - Dan E. Moldea