Gaspipe Casso was quite a nasty guy and a homicidal maniac, ordering virtually anyone who crossed them or were purported informants to be rubbed out. May have killed 50 people, and reportedly behind 80-100 hits.

Anthony Accetturo even said of Casso, "all he wanted to do is kill, kill, get what you can, even if you didn't earn it."

Greg Scarpa was another notorious hitman (80-100 hits), and so was Carmine Persico.