It's in "The Telltale Moozadell," at Carmela's birthday celebration.

Tony offers Aaron champagne, which he declines due to God not wanting us to be drinking. Tony points out that Jesus drank wine, to which Janice chimes in about Jesus being Jesus. Tony notices the hunk of booger sugar on her nose, and very unsubtlely points it out.

Speaking of Carmela's birthday, what ungrateful kids she raised.