Here in Britain the media has vilified Knox but our media is arguably the worlds biggest stirrer.
I think the USA may extradite her simply to keep the peace because if they refuse the next time the USA requests extradition from another country they may get rebuffed
We already are getting rebuffed by North Korea. Russia isn't handing over Plowden to us either and that guy leaked national secrets.
Italy is in a turmoil with its economy so they aren't exactly in the position to demand us to hand her over.