Say you were an up and coming mobster and could somehow take control of a family (active or defunct) and build it back to prominence, which would you choose? Being from the south I would pick New Orleans because it would be nice to have a strong southern LCN family. Outside of that I think the Colombo family in NYC would be a good choice. They are one of the weaker "five" but they have a strong history and it'd be cool to see them rise up after the Persico regime comes to an end.