TIS, we have friends who are in their early 60s. They live almost two hours away, so we only see them a few times a year. The last couple of times we've seen them, I've noticed that the wife repeated things, and asked me the same question about my daughters several times. I wondered if she might be exhibiting the first signs.

My grandmother was living on her own and in good health when she fell and broke her hip. While in the hospital, she completely lost her memory and never recovered, either mentally or physically. She spent her last few years in a wheelchair, and it was pitiful because some days she couldn't even remember her own name. It was odd that she could remember that she had a son and daughter, she could recall their names, but if my father told her that he was her son, she would deny it.