I am running TuneUp Utilities Pro, Malwarebytes Pro, and ESET NOD32 Antivirus Pro (best in my opinion).

With these three programs I have been able to manage my PC mroe than adequately, my computer runs in tip top shape, no viruses/malware/trojans,etc in all three years that I have had it which is great considering I am constaly streaming,downloading music and videos on it.

Note: I didnt pay for any of the aforementioned software even though I have the pro/premium versions which require payment. I used an old friend called Google to search warez sites for them and for serial numbers, etc.