Hubert Sumlin, the guitarist whose slashing solos and innovative ideas galvanized the blues of Howlin’ Wolf and inspired rock guitar players like Jimmy Page, Robbie Robertson and Eric Clapton, died on Sunday in Wayne, N.J. He was 80.

His death was announced on his official Web site, hubertsumlinblues.com. No cause was specified.

Mr. Sumlin began appearing on Howlin’ Wolf’s recordings in 1953, first as a rhythm guitarist and then, beginning in 1955, on lead guitar. Mr. Sumlin’s eerie guitar counterpart to Howlin’ Wolf’s unearthly moaning on the 1956 hit “Smokestack Lightnin’ ” has lately been featured in a television commercial for Viagra. He also played lead on “Back Door Man,” “Spoonful” and “The Red Rooster,” all written and arranged by the Chicago blues trailblazer Willie Dixon.

“Dixon’s often astute novelty lyrics and shrewd arrangements were topped off by Sumlin’s imaginative, angular, taut attack, frequent glisses, maniacally wide vibrato and percussive chords, all drawn with an exaggerated brush,” the producer Dick Shurman observed of Mr. Sumlin’s relentlessly inventive playing in his liner notes to a 1991 boxed set of Howlin’ Wolf’s work for Chess Records....