No matter who they choose to take Sheen's place, assuming they will continue the show, I just can't see it being successful. The show has had a long run with Sheen comfortably in the lead. I don't see it continuing with anyone else even if they lose the Charlie Harper"character" and add Lowe or Stamos (who I can actually picture doing Sheen's role)as the long lost Harper cousin or whatever......I think it's over if Charlie is gone. Its ran its course.

TIS