Lepke had alliances with various Mafiosi, so it's not inconceivable that the Luccheses may have had some action in the Garmend Center during Lepke's lifetime. But I doubt it amounted to much, if anything. His primary ally was the Mangano/Anastasia family. The Luccheses got a big piece of the action after the Gambino/Lucchese wedding you referred to, which occurred years after Lepke went to the electric chair.