La Cosa Nostra means "Our Thing" and is the name of the Commission that Charles Lucciano established following the Castellammarese War.

La Cosa Nostra consists of the heads of the five New York families, as well as other bosses from around the country. At the time, Buffalo and Chicago were also involved with the Commission.

Lucciano established the Commission to bring order to prevent another war. All major hits have to be approved by the Commission.