I base my hypothesis on world events and the direction I see things going. Without going too much into politics I would suggest a look into the sociopolitical conditions that prompted the formation of cosa nostra [ and similar groups ], and compare that to the direction we are headed. I see a nearly identical pattern.

I strongly suspect we will see a demand for black markets due to increased prohibitions, rationing, and mandates. Where there is a demand, it will be met by the market. LCN is, essentially, a market driven phenomenon. Where government creates restrictions that contradict market demand, that demand doesnt just 'go away'. It goes around the government and black markets are created which are inevitably organized and controlled by groups which operate outside the law. LCN and most other organized crime groups are, essentially, an outgrowth of the will of the people where that will is stifled by a government leadership which does not reflect it.

Prohibition is a perfect example of that, and so is the iron handed totalitarian regimes in communist Russia which gave birth to a black market economy and the Russian mob. The same is going to happen here. Cosa Nostra will find itself needed again, only this time you may see guys being prosecuted for smuggling hams and bread, instead of heroine and hookers.