With the Vegas skim, it's arguable that the Outfit was the most powerful mafia family in the 1970's. I'd imagine another time the Outfit was arguably the most powerful mob family was in the 1930s. There's a reason Lucky and the guys in NY allowed Chicago on the commission, and if you read a lot of Mario Puzo, it's probably not because they liked Chicago...
If you look at the known figures, the Vegas skim wasn't nearly enough to be a factor to put the Outfit on top. Not in the 1950s and 1960s and certainly not afterward. And it's always been the Genovese who were the most powerful. I don't know how anyone can argue otherwise.