for me her most irritating moment was when tony and paulie were going on the lam for a little while she got all pissy, saying "this is what life is like, at our age?"
what the hell would you expect? just because she didn't know the specifics didn't mean she doesn't know he was committing crimes pretty much daily. she's definitely one of the more contemptible characters.
Because Carmela wishfully thought that maybe Tony would be like one of those Carlo Gambino mobsters that would end up dying an old man in his own bed, like any mob wife would wishfully think.