Let's see since this question have been asked before.
The drug trafficking aspect is where Frank Matthews & Ike Atkinson excelled in more so than the NYC families. In general rackets the NYC families have more diverse income and their honey & milk rackets won't rely on a foreign source.
Comparing a Kingpin's operation to an individual or collective NYC family (ies) is hardly comparable. They're a few structured groups in NYC underworld that have maintained which will be the prison gangs & bikers.