According to an expert named "Google":
Vito is based on Frank Costello and Carlo Gambino.
Michael is based on Joe Bonanno and Vito Genovese.
Hyman Roth: Meyer Lanskey
Moe Greene: Bugsy Siegel
Johnny Fontaine: Kanye West. duh.
"...the successful annihilation of organized crime's subculture in America would rock the 'legitimate' world's foundation, which would ultimately force fundamental social changes and redistributions of wealth and power in this country. Meyer Lansky's dream was to bond the two worlds together so that one could not survive without the other." - Dan E. Moldea
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