Unless such sanctions occasion a change in Iran's government, Iran can wait until the sanctions decrease or expire and then reengage their nuclear efforts years down the road.
True. Regime change was/is one of the goals of sanctions.
What is never mentioned during any talk shows or news broadcasts is the inevitability of war with Iran if the West's non-belligerent remedies fail.
Nobody wants war with Iran, starting with Israel. But if they get nuclear weapons, preventive military action may be inevitable. And if it comes to that, I'd bet it'd be led by Saudi Arabia, Egypt or Turkey.