What do I think about Profaci? One can only guess. My guess is that he was primarily a drug trafficker with unique drug trafficking connections stretching back to his native village of Villabate in Sicily. I have no basis for believing that though.
The Gallos were being backed by other bosses of other families so that those bosses together with the Gallos could take over Profaci's drug trafficking operations. In other words, the Gallo-Profaci war was a drug war. But again, I have no basis for that supposition.