Try 115 Madison Street which is just southeast of little Italy near the manhattan bridge. It was Lefty Ruggieros club. Across the street at 116 Madison was the Holiday Bar which was owned by Tony Mirra (I believe). Also, the apartment complex right behind Madison street on Monroe street is called knickerbocker village and is where ruggiero, mirra and Richard cantarella grew up. Cantarella ran the New York Post distribution center, also in that area.
While your there, might as well check out the old Fulton Fish Market, a few blocks away.