There is. There is always room for good story and good characters. Good writing is good writing.

The bad part about success is that it is copied constantly. I'm sure after The Sopranos, tons of pilots were written about the mafia and a sort of new angle to make it unique.

For the most part it takes time between certain niche stories for the audience to get back into it.

BUT look at zombie stories. There have always been zombie stories and there is a huge niche audience for them, like the mafia, but the Walking Dead is doing a very bare bones, throwback version of the zombie story. So, IMO, anything can be done, it just has to be done well.

Alot of stuff is timing. Things hit the zeitgeist and it blows up, you never know.