What I found so interesting about that list you provided were the smaller families...glorified crews that were big into drugs
Though obviously not as big of an income producer for them as gambling, drugs to seem to be a staple for the New England and Philadelphia families. Not so much the case with New Jersey or Chicago. As for the others, I don't know if I would say they were "big" into drugs. Well, the Trafficante operation had smuggled $80 million worth of marijuana from Mexico but that was over a 15 year period.