I will go borough by borough. Some of these may not be the toughest now, but overall toughest reputation over the years :

Manahattan : Hell's Kitchen

Queens : Hollis

Da Bronx : Fordham & Fort Apache Section

Staten Island : Stapleton

Brooklyn : East New York

As for Avenue J in Brooklyn...." I eat Avenue J."
lol



Don Cardi cool

Five - ten years from now, they're gonna wish there was American Cosa Nostra. Five - ten years from now, they're gonna miss John Gotti.