In a post-Pot legalized America, it would be no different in dealing with it than we already are with drunks, glue-sniffers, etc.

This won't give potheads a license to be indisposed or high at work or in public. If you're high at work, you'll get fired. If you're high while driving, you're gonna a free bed for the night courtesy of the police.

The late conservative William Buckley (founder of National Review) himself turned to pro-legalization in the mid-1990s and (with others) penned this editorial arguing why the "War on Drugs" was lost.

http://old.nationalreview.com/12feb96/drug.html