Yeah, that dude came to a pretty messy end, didn't he?
Marcello & Trafficante? Giancana had just been taken out, the other link in the Castro/CIA plot. Would bosses such as they have needed permission, per say? Would they have needed to have their plot sanctioned by the Outfit? Marcello was pretty powerful in his heyday, but was that power confined to New Orleans? Trafficante maybe.

Yeah, interesting guy, old Filippo Sacco. Funny how he gets thrown into the Kennedy Assasination.