How did House hurt his leg?

he suffered an infarction in his right leg, which went misdiagnosed for three days due to doctors' concerns that he was exhibiting drug-seeking behavior (House eventually diagnosed the infarction himself). An aneurysm in his thigh had clotted, leading to an infarction and causing his quadriceps muscle to become necrotic. House had the dead muscle bypassed in order to restore circulation to the remainder of his leg, risking organ failure and cardiac arrest. He was willing to endure excruciating post-operative pain to retain the use of his leg. After House was put into a chemically induced coma to sleep through the worst of the pain, Stacy, House's medical proxy, acted against his wishes and authorized a safer surgical middle-ground procedure between amputation and a bypass by removing just the dead muscle. This resulted in the partial loss of use in his leg, and left House with a lesser, but still serious, level of pain for the rest of his life. House could not forgive Stacy for making the decision, so because of this, Stacy left him.[23] House now suffers chronic pain in his leg, uses a cane to aid his walking, and takes Vicodin (hydrocodone) frequently to relieve his pain.