Michael Owen is expected to miss out on a place in England boss Fabio Capello's starting line-up for the Italian's first game in charge on Wednesday.
The striker is set to be on the bench for the friendly against Switzerland.
Capello had Joe Cole operating behind Wayne Rooney up front in his final training session on Tuesday.
Matthew Upson joined Rio Ferdinand in central defence, with David Bentley and Ashley Young alongside Owen Hargreaves and Steven Gerrard in midfield.
With David James given the nod in goal, if that line-up took the field on Wednesday, only temporary captain Steven Gerrard and Joe Cole would remain from the team beaten 3-2 by Croatia in Steve McClaren's last game at the helm.
Capello has vowed not to tell his players who is in the team until shortly before they leave their hotel for Wembley on Wednesday afternoon.
Newcastle star Owen, who has scored 40 goals in 88 appearances for his country, has only just returned to first-team action after a succession of injuries.
Young, 22, would be making only his second appearance for the England senior team but he has enjoyed an impressive season with Aston Villa.
606: DEBATE Who should start for England ?
He would start in the left side of midfield, with 23-year-old Bentley on the right.
The Blackburn Rovers player, who has played twice for England, has long been tipped to fill a role that David Beckham had been hoping to occupy.
But new boss Capello decided the Los Angeles Galaxy midfielder would have to wait until he was fully match fit before being given the chance to win his 100th cap.
James appears to have beaten off competition from Villa's Scott Carson and Wigan's Chris Kirkland to start in goal.
The 37-year-old, who has been in tremendous form for Portsmouth this season, will be earning his 36th cap.
In front of him, Upson would be making his first England appearance since coming on a substitute in the 1-0 defeat by Spain in Madrid on 17 November 2004.
And Manchester United's Wes Brown looks to have landed the right-back berth ahead of Micah Richards.
Expected team: David James (Portsmouth), Wes Brown (Manchester United), Rio Ferdinand (Manchester United), Matthew Upson (West Ham), Ashley Cole (Chelsea); David Bentley (Blackburn), Steven Gerrard (Liverpool), Owen Hargreaves (Manchester United), Ashley Young (Aston Villa); Joe Cole (Chelsea), Wayne Rooney (Manchester United).
The Mafia Is Not Primarily An Organisation Of Murderers. First And Foremost,The Mafia Is Made Up Of Thieves. It Is Driven By Greed And Controlled By Fear.
Between The Law And The Mafia, The Law Is Not The Most To Be Feared
"What if the Mafia were not an organization but a widespread Sicilian attitude of hostility towards the law?"
