I'm in the middle of a Sopranos retrospective. It's positively the greatest thing I've ever seen.
I'd like to get into Arrested Development and Freaks and Geeks, and need also to start watching Seinfeld.
I bought season one of The Wire, upon Kino and other people's recommendations. Haven't started it yet, though; I want to finish Sopranos first, and then head into it fresh.