What about Melfi? No one in this show is safe. I can see it now...

Episode 86, "Made in America" Final Scene

Melfi- Why all this anger, Anthony?
Tony- I can't trust anybody, not even my best friends
Melfi- Why?
Tony- I won't go into detail, but they've dissapointed me
Melfi- Well usually when friends anger one another they resolve these issues or they move on
Tony- I've chose the latter recently...
Melfi- Anthony, you realize you ARE your mother! Anything anybody does for you is not good enough for you. Only you're a criminal that lies and kills and...
(Tony pulls out a gun)
Tony- Shut the fuck up!
(Fires the gun, bullet hits Melfi in the forehead)
Tony- Bitch...
(Tony leaves the office, walks outside and starts staring at the sky)
Screen fades to black