Haven't got to play the game a whole lot since I bought it with work and all, but what I've seen, I've definately liked!

I don't really need any help yet, but I was wondering if there is any disadvantage to completing all the missions before you extort and take over rackets/warehouses, compounds, etc? I have been doing them both at the same regularity, but have really found myself wanting to continue with the movie missions first just because I can't wait to see what how they'll correspond to the movies. Thanks.