If you compare before and after pictures of any president (before and after taking office), you will see how incredibly they've all aged. I know that after 8 years, we would all show some aging, but they all seem to age INCREDIBLY. I would say that Carter probably aged the most while in office, and Nixon the least. The stress of that job has to be huge.
And speaking of Clinton, does anyone else seem to think that he really hasn't bounced back after his open-heart surgery?? He looks awful. It might be the weight loss, which never looks good on someone his age, but I think that he still may not have fully recovered.